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Grape Seed Extract

Preliminary EvidenceEducational only · ManCore does not sell supplements

What the evidence shows

Rich in proanthocyanidins with solid evidence for vascular and antioxidant benefits generally, but limited direct human trial data specific to testosterone or male sexual health outcomes. Best framed as a general cardiovascular-support supplement with plausible but unproven downstream relevance to erectile blood flow.

How it's thought to work

Potent antioxidant polyphenols that support endothelial function and reduce oxidative stress in vascular tissue.

Typical Dosage

150–300mg/day of a standardized extract.

Safety Notes

Generally very safe. Mild blood-thinning effect possible at higher doses.

Want the full clinical breakdown?

Grape seed extract inhibits aromatase in laboratory studies and lowers blood pressure modestly in human trials, but no human trial shows that it raises testosterone.

Read the full evidence review

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